Mpox

Current Outbreak Summary

Update as of October 21, 2024 

The mpox virus is classified into 2 main clades, clade I and clade II, with each further subdivided into clade Ia, the newly identified clade Ib, clade IIa, and clade IIb, the clade which was responsible for the 2022 global outbreak. Since the 2022 clade IIb mpox outbreak began, there have more than 106,310 cases and more than 234 deaths reported in 123 countries, though world-wide reported data likely do not include the most recent outbreaks of clade I in the Africa region. According to the US Centers for Disease Control and Prevention (US CDC) and the World Health Organization (WHO), the US has reported 34,063 mpox cases as of August, 2024. The US outbreak has continued to grow at a low but steady pace in 2024, with 2,415 cases recorded year to date as of October 12, 2024. With the continued transmission of clade IIb in the US and globally and the increased transmission of clade I and II in the Africa region, experts are concerned that changes in the national and global landscape have the potential to increase health risks for specific US populations.